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Journal Textile Coloration and Finishing
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2021 / V.33,no.4,Dec
Title A Study on the Preparation of 5(6)-Carboxyflurescein–supported Phospholipid Liposomes and Evaluation of Bacterial Sensing Ability
Authors Minho Han, Jaewoo Jeon1, Junyoung Lee1, Eunsuk Shin1, Woojin Kim1, and Samsoo Kim*
Institution/Affiliations Yeungnam University, 1DYETEC Institute
Pages/Total page pp.338 ~ 347 / 10
Language Korean
Abstract In the case of occlusive dressings currently used in dressings for burn treatment, it is impossible to confirm the replacement time, so replacement is delayed, resulting in additional infection. To solve this problem, liposomes capable of bacterial sensing were prepared using 5(6)-Carboxyfluorescein, Phosphatidylcholine, 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine, Cholesterol, and 10,12-Tricosadiynoic acid. In this study, evaluation of changes in drug encapsulation rate in liposomes according to changes in three types of phosphatidylcholine phospholipids during liposome production, high-performance phosphatidylcholine phospholipids selected through vesicle size analysis, low and high temperature stability evaluation, bacterial sensitization ability evaluation, animals cell responses were assessed.
Keywords liposome, lipid vesicle, phospholipid, bacterial sensing, burn wound, occlusive dressing
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Reference http://koreascience.or.kr/journal/OSGGBT.page?&lang=ko

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