|
|
|
|
|
Journal |
Textile Coloration and Finishing |
Year / Vol., Issue, Month |
2018 / V.30,no.2,Jun |
Title |
Preparation and Biocompatibility of Medical Fiber from Novel
Regenerated Cellulose from Styela clava tuni |
Authors |
Sung Hwa Song, Ji Eun Kim, Jun Young Choi, Jin Ju Park, Mi Rim Lee, Bo Ram Song, Yechan Lee, Hong Sung Kim, Jae Ho Lee, Yong Lim1, Dae Youn Hwang and Young Jin Jung |
Institution/Affiliations |
Pusan National University, Dong-Eui University |
Pages/Total page |
pp.117 ~ 129 / 13 |
Language |
Korean |
Abstract |
Abstract Cellulose has been widely applied into various medical fields including scaffolding,
tissue engineering and tissue formation. In this study, we manufactured cellulose
medical fiber from Styela clava tunics(SCT-CS) and analyzed the tensile strength, elongation
at break, fluid uptake and surface morphology. And then, the biocompatibility and
toxicity of SCT-CS were measured in Sprague-Dawley(SD) rats after the implantation for
30, 60 and 90 days. The level of tensile strength and fluid uptake were lower in SCT-CS
than chromic catgut(CCG), while elongation at break level were maintained the higher in
SCT-CS. Also, the roughness with pronounced surface patterns as a result of in vivo
degradation was significantly greater in CCG than this of SCT-CS although these levels
gradually appeared with time in both groups. After implantation for 90 days, SCT-CS and
CCG was successfully implanted around muscle of thigh without any significant immune
response. Furthermore, no significant alterations were measured in serum parameters
and the specific pathological features induced by most toxic compounds for liver and kidney
toxicity. Therefore, these results suggest that SCT-CS showing good biocompatibility
and non-toxicity can be successfully prepared from cellulose powder of SCT as well as
has the potential for use as a powerful biomaterial for medical sutures. |
Keywords |
Keywords medical fibers, cellulose, Styela clava tunics, physical properties, biocompatibility |
Download |
|
Reference |
http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=OSGGBT_2018_v30n2_117&ordernum= |
|
|
|
|
|
|
|
|
|